AffyRNADegradation

Analyze and correct probe positional bias in microarray data due to RNA degradation


Bioconductor version: Release (3.20)

The package helps with the assessment and correction of RNA degradation effects in Affymetrix 3' expression arrays. The parameter d gives a robust and accurate measure of RNA integrity. The correction removes the probe positional bias, and thus improves comparability of samples that are affected by RNA degradation.

Author: Mario Fasold

Maintainer: Mario Fasold <fasold at izbi.uni-leipzig.de>

Citation (from within R, enter citation("AffyRNADegradation")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("AffyRNADegradation")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("AffyRNADegradation")
AffyRNADegradation Example PDF R Script
Reference Manual PDF
NEWS Text

Details

biocViews GeneExpression, Microarray, OneChannel, Preprocessing, QualityControl, Software
Version 1.52.0
In Bioconductor since BioC 2.10 (R-2.15) (12.5 years)
License GPL-2
Depends R (>= 2.9.0), methods, affy
Imports
System Requirements
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Suggests AmpAffyExample, hgu133acdf
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package AffyRNADegradation_1.52.0.tar.gz
Windows Binary (x86_64) AffyRNADegradation_1.52.0.zip
macOS Binary (x86_64) AffyRNADegradation_1.52.0.tgz
macOS Binary (arm64) AffyRNADegradation_1.52.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/AffyRNADegradation
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/AffyRNADegradation
Bioc Package Browser https://code.bioconductor.org/browse/AffyRNADegradation/
Package Short Url https://bioconductor.org/packages/AffyRNADegradation/
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