kmcut

Optimized Kaplan Meier analysis and identification and validation of prognostic biomarkers


Bioconductor version: Release (3.20)

The purpose of the package is to identify prognostic biomarkers and an optimal numeric cutoff for each biomarker that can be used to stratify a group of test subjects (samples) into two sub-groups with significantly different survival (better vs. worse). The package was developed for the analysis of gene expression data, such as RNA-seq. However, it can be used with any quantitative variable that has a sufficiently large proportion of unique values.

Author: Igor Kuznetsov [aut, cre], Javed Khan [aut]

Maintainer: Igor Kuznetsov <ibkalb at gmail.com>

Citation (from within R, enter citation("kmcut")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("kmcut")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("kmcut")
kmcut_intro HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews GeneExpression, Software, StatisticalMethod, Survival
Version 1.0.0
In Bioconductor since BioC 3.20 (R-4.4) (< 6 months)
License Artistic-2.0
Depends
Imports survival, tools, methods, pracma, doParallel, foreach, parallel, SummarizedExperiment, S4Vectors
System Requirements
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Suggests BiocStyle, knitr, rmarkdown
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package kmcut_1.0.0.tar.gz
Windows Binary (x86_64) kmcut_1.0.0.zip
macOS Binary (x86_64) kmcut_1.0.0.tgz
macOS Binary (arm64) kmcut_1.0.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/kmcut
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/kmcut
Bioc Package Browser https://code.bioconductor.org/browse/kmcut/
Package Short Url https://bioconductor.org/packages/kmcut/
Package Downloads Report Download Stats